Selenbp1 Gene Summary [Rat]

Predicted to enable methanethiol oxidase activity. Predicted to be involved in protein transport. Predicted to act upstream of or within brown fat cell differentiation. Predicted to be located in fibrillar center. Orthologous to human SELENBP1 (selenium binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Selenbp1
Official Name
selenium binding protein 1 [Source:RGD Symbol;Acc:620571]
Ensembl ID
ENSRNOG00000047158
Bio databases IDs NCBI: 103689947 Ensembl: ENSRNOG00000047158
Aliases selenium binding protein 1
Synonyms EHMTO, HEL-S-134P, hSBP, LPSB, MTO, rSBP, SBP56, SELENBP2, selenium binding protein 1, SP56
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Selenbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 56kDa selenium binding protein (SBP56)
  • enzyme
  • protein binding
  • selenium binding
  • methanethiol oxidase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
  • lung adenocarcinoma
  • Alzheimer disease
  • colorectal cancer
  • extraoral halitosis due to methanethiol oxidase deficiency
  • COVID-19
  • organismal death
  • lung adenocarcinoma formation
  • extra oral halitosis
  • androgenic alopecia
regulated by
  • dexamethasone
  • dihydrotestosterone
  • beta-estradiol
  • cobalt chloride
  • ALOX5
  • PC-SPES
  • FOS
  • GNA14
  • RAF1
  • heavy metal
role in cell
  • apoptosis
  • proliferation
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • fibrillar center
  • cytosol
  • nucleoli
  • exosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Selenbp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular vesicular exosome
  • membrane
  • cytosol
  • nucleolus
  • fibrillar center

Molecular Function

What the gene product does at the molecular level
  • methanethiol oxidase activity
  • protein binding
  • selenium binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.