Dnajc16 Gene Summary [Rat]

Predicted to be involved in regulation of autophagosome size. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Dnajc16
Official Name
DnaJ heat shock protein family (Hsp40) member C16 [Source:RGD Symbol;Acc:1359395]
Ensembl ID
ENSRNOG00000012503
Bio databases IDs NCBI: 362652 Ensembl: ENSRNOG00000012503
Aliases DnaJ heat shock protein family (Hsp40) member C16
Synonyms 2900037O03RIK, 4732437J24Rik, D030060M24, DnaJ heat shock protein family (Hsp40) member C16, ERdj8, mKIAA0962
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dnajc16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • DnaJ domain
  • DnaJ
  • DnaJ molecular chaperone homology domain
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

Pathways

Biological processes and signaling networks where the Dnajc16 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • kidney carcinoma
  • renal cancer
  • hereditary spastic paraplegia
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
  • alcoholic pancreatitis
  • cough
  • gout
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Dnajc16 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of autophagic vacuole size

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.