Cyp2c23 Gene Summary [Rat]
Enables arachidonate 11,12-epoxygenase activity and arachidonate 14,15-epoxygenase activity. Involved in epoxygenase P450 pathway; icosanoid biosynthetic process; and response to testosterone. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cyp2c23 |
| Official Name | cytochrome P450, family 2, subfamily c, polypeptide 23 [Source:RGD Symbol;Acc:620370] |
| Ensembl ID | ENSRNOG00000013291 |
| Bio databases IDs | |
| Aliases | cytochrome P450, family 2, subfamily c, polypeptide 23 |
| Synonyms | Aa epoxygenase, Arachidonic Acid Epoxygenase, b2b386Clo, BC034834, Cyp2c44, cytochrome P450, family 2, subfamily c, polypeptide 23 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cyp2c23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome P450 (CYP) superfamily
- Cytochrome P450
- arachidonic acid 11,12-epoxygenase
- arachidonic acid 14,15-epoxygenase
- monooxygenase
- enzyme
- arachidonic acid epoxygenase
Pathways
Biological processes and signaling networks where the Cyp2c23 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cancer
- metastasis
- neoplasia
- esophageal adenocarcinoma
- esophageal carcinoma formation
- advanced cancer
- Barrett syndrome
role in cell
- expression in
- downregulation in
- number
- phagocytosis by
- efferocytosis by
- upregulation in
- efferocytosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
- microsome