Rps2 Gene Summary [Rat]
A structural constituent of ribosome. Involved in formation of translation preinitiation complex; response to ethanol; and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Orthologous to human RPS2 (ribosomal protein S2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps2 |
| Official Name | ribosomal protein S2 [Source:RGD Symbol;Acc:619887] |
| Ensembl ID | ENSRNOG00000014179 |
| Bio databases IDs | |
| Aliases | ribosomal protein S2 |
| Synonyms | Cho-B, LLREP3, Ribosomal protein s2, Rps2r1, RPS4, S2, S4, uS5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rps2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- binding protein
- fibroblast growth factor binding
- mRNA binding
- Ribosomal protein S5, N-terminal domain
- ribosomal protein uS5, eukaryotic/archaeal form
- enzyme binding
- protein binding
- Ribosomal protein S5, C-terminal domain
Pathways
Biological processes and signaling networks where the Rps2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- androgenic alopecia
- atrial fibrillation
- papillary thyroid carcinoma
- papillary thyroid cancer
regulates
- RNR
- PRKN
- Ribosomal Subunit 40s
- ubiquitin ligase
role in cell
- processing in
- response by
- nuclear export in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- ribosomal fraction
- detergent resistant lipid raft fraction
- ribosome
- Nucleus
- Mitochondria
- cytosol
- nucleoplasm
- nuclear envelope
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rps2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of ubiquitin-protein ligase activity
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- focal adhesion
- cytosolic ribosome
- cytosolic small ribosomal subunit
- cytoplasm
- membrane
- cytosol
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- cadherin binding
- mRNA binding
- fibroblast growth factor binding
- enzyme binding