C2cd5 Gene Summary [Mouse]
Enables calcium ion binding activity. Involved in insulin receptor signaling pathway; positive regulation of D-glucose transmembrane transport; and positive regulation of vesicle fusion. Acts upstream of or within positive regulation of D-glucose import; protein localization to plasma membrane; and vesicle fusion. Located in plasma membrane. Orthologous to human C2CD5 (C2 calcium dependent domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | C2cd5 |
| Official Name | C2 calcium-dependent domain containing 5 [Source:MGI Symbol;Acc:MGI:1921991] |
| Ensembl ID | ENSMUSG00000030279 |
| Bio databases IDs | |
| Aliases | C2 calcium-dependent domain containing 5 |
| Synonyms | 5730419I09Rik, C030008B15Rik, C2 calcium-dependent domain containing 5, CDP138, KIAA0528, RGD1304592 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse C2cd5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- calcium ion binding
- calcium-dependent phospholipid binding
- protein binding
- Protein kinase C conserved region 2 (CalB)
- Serine Proline motif
- C2 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic vesicle membrane
- cell cortex
- Plasma Membrane
- centrosome
- cytosol
- membrane ruffles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse C2cd5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of glucose transport
- positive regulation of protein targeting to membrane
- positive regulation of vesicle fusion
- insulin receptor signaling pathway
- intracellular protein transmembrane transport
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
- centriolar satellite
- cell cortex
- cytosol
- ruffle membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding
- calcium-dependent phospholipid binding