Cndp2 Gene Summary [Rat]

Predicted to enable dipeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Orthologous to human CNDP2 (carnosine dipeptidase 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cndp2
Official Name
carnosine dipeptidase 2 [Source:RGD Symbol;Acc:1305827]
Ensembl ID
ENSRNOG00000015591
Bio databases IDs NCBI: 291394 Ensembl: ENSRNOG00000015591
Aliases carnosine dipeptidase 2
Synonyms 0610010E05Rik, carnosine dipeptidase 2, CN2, CNDP dipeptidase 2, CPGL, Dip-2, HEL-S-13, HsT2298, PEP1, PEPA
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cndp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc peptidases M18, M20, M28, and M42
  • Peptidase family M20/M25/M40
  • dipeptidase
  • peptidase
  • cytosol nonspecific dipeptidase
  • acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • refractive error
  • COVID-19
  • acute myeloid leukemia
  • endometriosis
  • diabetes mellitus
  • breast cancer
regulated by
  • keratinocytes
  • progesterone
  • heavy metal
  • L-arginine
  • HMGA1
  • bestatin
regulates
  • CD44
  • lactic acid
  • CXCR3
  • L-phenylalanine
  • N-L-lactoyl-L-phenylalanine
  • MMP11
role in cell
  • expression in
  • cell viability
  • growth
  • production in
  • migration
  • G1 phase
  • invasion
  • colony formation
  • tumorigenicity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • nucleoplasm
  • exosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cndp2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • carboxypeptidase activity
  • metallodipeptidase activity
  • metal ion binding
  • dipeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.