Cndp2 Gene Summary [Mouse]
Enables dipeptidase activity. Acts upstream of or within proteolysis. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including 1st branchial arch; ear; limb; nervous system; and urinary system. Orthologous to human CNDP2 (carnosine dipeptidase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cndp2 |
| Official Name | CNDP dipeptidase 2 (metallopeptidase M20 family) [Source:MGI Symbol;Acc:MGI:1913304] |
| Ensembl ID | ENSMUSG00000024644 |
| Bio databases IDs | |
| Aliases | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| Synonyms | 0610010E05Rik, carnosine dipeptidase 2, CN2, CNDP dipeptidase 2, CPGL, Dip-2, HEL-S-13, HsT2298, PEP1, PEPA |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cndp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc peptidases M18, M20, M28, and M42
- Peptidase family M20/M25/M40
- dipeptidase
- peptidase
- cytosol nonspecific dipeptidase
- acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- refractive error
- COVID-19
- acute myeloid leukemia
- endometriosis
- diabetes mellitus
- breast cancer
regulated by
- keratinocytes
- progesterone
- heavy metal
- L-arginine
- HMGA1
- bestatin
role in cell
- expression in
- cell viability
- growth
- production in
- migration
- G1 phase
- invasion
- colony formation
- tumorigenicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- nucleoplasm
- exosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cndp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- carboxypeptidase activity
- metallodipeptidase activity
- metal ion binding
- dipeptidase activity