Rcn2 Gene Summary [Rat]

Predicted to enable calcium ion binding activity. Predicted to be located in nucleolus. Predicted to be active in endoplasmic reticulum. Orthologous to human RCN2 (reticulocalbin 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rcn2
Official Name
reticulocalbin 2 [Source:RGD Symbol;Acc:3548]
Ensembl ID
ENSRNOG00000015780
Bio databases IDs NCBI: 29218 Ensembl: ENSRNOG00000015780
Aliases reticulocalbin 2
Synonyms E6BP, ERC-55, Reticulocalbin 2, TCBP49
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rcn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EF-hand domain pair
  • calcium ion binding
  • EFh
  • EF-hand, calcium binding motif, found in CREC-EF hand family
  • protein binding
  • EFh_PI-PLC

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal cancer
  • peripheral arterial disease
  • suicide attempt
regulated by
regulates
  • Ca2+
  • ERK1/2
role in cell
  • activation in
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • endoplasmic reticulum lumen
  • nucleoli
  • phagosomes
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Rcn2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum lumen
  • endoplasmic reticulum
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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