Rcn2 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Predicted to be located in nucleolus. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including axial skeleton; brain ventricular layer; cranium; extraembryonic endoderm; and thyroid cartilage. Orthologous to human RCN2 (reticulocalbin 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Rcn2 |
| Official Name | reticulocalbin 2 [Source:MGI Symbol;Acc:MGI:1349765] |
| Ensembl ID | ENSMUSG00000032320 |
| Bio databases IDs | |
| Aliases | reticulocalbin 2 |
| Synonyms | E6BP, ERC-55, Reticulocalbin 2, TCBP49 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rcn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand domain pair
- calcium ion binding
- EFh
- EF-hand, calcium binding motif, found in CREC-EF hand family
- protein binding
- EFh_PI-PLC
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum lumen
- nucleoli
- phagosomes
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rcn2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- endoplasmic reticulum
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding