Hydin Gene Summary [Rat]
Predicted to be involved in axonemal central apparatus assembly and cilium movement. Predicted to act upstream of or within epithelial cell development; trachea development; and ventricular system development. Predicted to be located in axonemal central pair projection and sperm flagellum. Predicted to be active in axoneme. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 5. Orthologous to human HYDIN (HYDIN axonemal central pair apparatus protein). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hydin |
| Official Name | Hydin, axonemal central pair apparatus protein [Source:RGD Symbol;Acc:1562254] |
| Ensembl ID | ENSRNOG00000017178 |
| Bio databases IDs | |
| Aliases | Hydin, axonemal central pair apparatus protein |
| Synonyms | 1700034M11RIK, 4930545D19RIK, 4932703P14, A830061H17, AC069308.21gm4, CILD5, DKFZP434L0850, FLJ14665, Gm9558, hy-3, HYDIN1, HYDIN2, HYDIN axonemal central pair apparatus protein, HYDIN, axonemal central pair apparatus protein, hyrh, KIAA1864, PPP1R31 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hydin often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Arginine and glutamate-rich 1
- Cgr1 family
- Hydin Adenylate kinase-like domain
- Ezrin/radixin/moesin, alpha-helical domain
- UDM1_RNF168_RNF169-like
- protein binding
- PLC-beta C terminal
- Troponin
- MAP7 (E-MAP-115) family
- Chromatin assembly factor 1 complex p150 subunit, N-terminal
- Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
- ALMS motif
- Domain of unknown function (DUF4200)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- hypertension
- primary ciliary dyskinesia type 5
- celiac disease
- paroxysmal supraventricular tachycardia
- primary ciliary dyskinesia
- Alzheimer disease
- chronic obstructive pulmonary disease
- head and neck cancer
- myopia
regulates
role in cell
- development
- movement
- beat
- stalling
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- Mitochondria
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hydin gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ventricular system development
- trachea development
- epithelial cell development
- cilium movement
Cellular Component
Where in the cell the gene product is active
- axoneme