Mmp23 Gene Summary [Rat]
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in endoplasmic reticulum membrane and extracellular matrix. Predicted to be active in extracellular space. Orthologous to human MMP23B (matrix metallopeptidase 23B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mmp23 |
| Official Name | matrix metallopeptidase 23 [Source:RGD Symbol;Acc:620201] |
| Ensembl ID | ENSRNOG00000017477 |
| Bio databases IDs | |
| Aliases | matrix metallopeptidase 23 |
| Synonyms | CA-MMP, matrix metallopeptidase 23, matrix metallopeptidase 23B, MIFR, MIFR-1, MMP22, Mmp23, MMP23A, Mmp23bB |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mmp23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Matrixin
- ZnMc
- ShK domain-like
- immunoglobulin domain
- peptidase
- Zinc-dependent metalloprotease
- metalloendopeptidase
Pathways
Biological processes and signaling networks where the Mmp23 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- nuclear membrane fraction
- membrane fraction
- cell periphery
- perinuclear region
- ER-to-Golgi intermediate compartment
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mmp23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- extracellular matrix organization
- collagen catabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- extracellular space
- extracellular matrix
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- metalloendopeptidase activity
- metallopeptidase activity