Baiap3 Gene Summary [Rat]
Predicted to enable calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in several processes, including dense core granule maturation; regulation of GABAergic synaptic transmission; and regulation of secretion by cell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytosol. Predicted to be active in several cellular components, including GABA-ergic synapse; cytoplasmic vesicle; and trans-Golgi network membrane. Orthologous to human BAIAP3 (BAI1 associated protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Baiap3 |
| Official Name | BAI1-associated protein 3 [Source:RGD Symbol;Acc:10059729] |
| Ensembl ID | ENSRNOG00000017893 |
| Bio databases IDs | |
| Aliases | BAI1-associated protein 3 |
| Synonyms | BAI1-associated protein 3, BAP3, Gm937 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Baiap3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNARE binding
- phospholipid binding
- calcium ion binding
- protein binding
- Protein kinase C conserved region 2 (CalB)
- syntaxin binding
- C2 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
- cytosol
- trans Golgi network
- endosomal membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Baiap3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of behavior
- G-protein coupled receptor signaling pathway
- positive regulation of neurotransmitter secretion
- positive regulation of insulin secretion involved in cellular response to glucose stimulus
- retrograde transport, endosome to Golgi
- regulation of synaptic transmission, GABAergic
- exocytosis
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- late endosome membrane
- cytosol
- dense core granule
- recycling endosome membrane
- plasma membrane
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- calcium ion binding
- SNARE binding
- phospholipid binding