Cfap100 Gene Summary [Rat]

Predicted to be active in ciliary basal body. Orthologous to human CFAP100 (cilia and flagella associated protein 100). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cfap100
Official Name
cilia and flagella associated protein 100 [Source:RGD Symbol;Acc:1305768]
Ensembl ID
ENSRNOG00000017959
Bio databases IDs NCBI: 297444 Ensembl: ENSRNOG00000017959
Aliases cilia and flagella associated protein 100
Synonyms C030041G11RIK, C230069K22Rik, CCDC37, cilia and flagella associated protein 100, Coiled-coil domain-containing protein 37, MIA1, RGD1305768
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cfap100 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • protein binding
  • Domain of unknown function (DUF4200)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
regulated by
  • dexamethasone
  • filgrastim

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • motile cilia
  • basal bodies
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cfap100 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium movement
  • inner dynein arm assembly

Cellular Component

Where in the cell the gene product is active
  • motile cilium
  • cilium basal body

Molecular Function

What the gene product does at the molecular level
  • dynein complex binding

Gene-Specific Assays for Results You Can Trust

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