Mrto4 Gene Summary [Rat]

Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human MRTO4 (MRT4 homolog, ribosome maturation factor). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mrto4
Official Name
MRT4 homolog, ribosome maturation factor [Source:RGD Symbol;Acc:1311709]
Ensembl ID
ENSRNOG00000017979
Bio databases IDs NCBI: 298586 Ensembl: ENSRNOG00000017979
Aliases MRT4 homolog, ribosome maturation factor
Synonyms 2610012O22Rik, C1orf33, dJ657E11.4, Mg684, mRNA turnover 4, ribosome maturation factor, MRT4, MRT4 homolog, ribosome maturation factor, RGD1311709
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrto4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal_L10_P0
  • Ribosomal protein L10
  • Insertion domain in 60S ribosomal protein L10P
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • lactacystin
  • IACS-010759
  • Z-LLL-CHO
  • TP53
  • fulvestrant
  • BCR (complex)
  • PPARG
  • TGFB1
  • let-7 (includes others)
  • TCF4
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrto4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal large subunit biogenesis
  • nuclear-transcribed mRNA catabolic process
  • rRNA processing

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • nucleolus
  • preribosome, large subunit precursor

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.