Mrto4 Gene Summary [Mouse]
Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in genitourinary system; liver lobe; pancreas; and submandibular gland primordium. Orthologous to human MRTO4 (MRT4 homolog, ribosome maturation factor). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Mrto4 |
| Official Name | mRNA turnover 4, ribosome maturation factor [Source:MGI Symbol;Acc:MGI:1917152] |
| Ensembl ID | ENSMUSG00000028741 |
| Bio databases IDs | |
| Aliases | mRNA turnover 4, ribosome maturation factor |
| Synonyms | 2610012O22Rik, C1orf33, dJ657E11.4, Mg684, mRNA turnover 4, ribosome maturation factor, MRT4, MRT4 homolog, ribosome maturation factor, RGD1311709 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrto4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal_L10_P0
- Ribosomal protein L10
- Insertion domain in 60S ribosomal protein L10P
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrto4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal large subunit biogenesis
- nuclear-transcribed mRNA catabolic process
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nucleolus
- preribosome, large subunit precursor
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding