Tpsb2 Gene Summary [Rat]
Predicted to enable heparin binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Orthologous to several human genes including TPSB2 (tryptase beta 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tpsb2 |
| Official Name | tryptase beta 2 [Source:RGD Symbol;Acc:3065] |
| Ensembl ID | ENSRNOG00000018611 |
| Bio databases IDs | |
| Aliases | tryptase beta 2 |
| Synonyms | AV011504, Clara tryptase, Mcp-6, Mcpt6, MMCP-6, tryptase beta 2, Tryptase Clara, tryptase β 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tpsb2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- peptidase
- Domain of unknown function (DUF1986)
- protein binding
- heparin binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- weight loss
- arthritis
- pulmonary emphysema
- colitis
- infection by parasite
role in cell
- apoptosis
- differentiation
- accumulation in
- chemotaxis
- recruitment
- morphology
- composition
- clearance
- integrity
- necrosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Nucleus