Ppfibp2 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to be involved in neuromuscular junction development. Is active in presynapse. Orthologous to human PPFIBP2 (PPFIA binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppfibp2 |
| Official Name | PPFIA binding protein 2 [Source:RGD Symbol;Acc:1565383] |
| Ensembl ID | ENSRNOG00000019667 |
| Bio databases IDs | |
| Aliases | PPFIA binding protein 2 |
| Synonyms | Cclp1, LOC102723874, PPFIA binding protein 2, PTPRF interacting protein, binding protein 2 (liprin beta 2), PTPRF interacting protein, binding protein 2 (liprin β 2) |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppfibp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sterile alpha motif
- SAM (Sterile alpha motif )
- SAM domain (Sterile alpha motif)
- phosphatase
- coiled-coil domain
- protein binding
- identical protein binding
- liprin homology domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- bronchopathy
- tuberculosis
- epithelial cancer
- dementia
- prostatic carcinoma
- prostate cancer
- non-small cell lung carcinoma
- non-small cell lung cancer
- neuroendocrine neoplasm
- neoplasia
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- presynaptic regions
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ppfibp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuromuscular junction development
Cellular Component
Where in the cell the gene product is active
- extracellular space
- presynaptic active zone
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding