Snap29 Gene Summary [Rat]
Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in regulation of synaptic vesicle cycle and regulation of synaptic vesicle exocytosis. Located in terminal bouton. Is active in synaptic vesicle. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Orthologous to human SNAP29 (synaptosome associated protein 29). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snap29 |
| Official Name | synaptosome associated protein 29 [Source:RGD Symbol;Acc:620225] |
| Ensembl ID | ENSRNOG00000001867 |
| Bio databases IDs | |
| Aliases | synaptosome associated protein 29 |
| Synonyms | 1300018G05Rik, CEDNIK, Gs32, synaptosomal-associated protein 29, synaptosome associated protein 29 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snap29 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNAP receptor
- Helical region found in SNAREs
- coiled-coil domain
- protein binding
- SNARE motif
- syntaxin binding
Pathways
Biological processes and signaling networks where the Snap29 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- human papilloma virus infection
- cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome, cednik syndrome
- hereditary disorder
- Pelizaeus-Merzbacher-like disease
- Duchenne muscular dystrophy
- oral cancer
role in cell
- killing
- degradation in
- synaptic transmission
- production in
- expression in
- proliferation
- number
- replication in
- attachment
- trafficking
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosolic synaptosomal fraction
- plasma membrane fraction
- membrane fraction
- cilia
- cellular membrane
- Plasma Membrane
- vesicles
- centrosome
- Golgi Apparatus
- Mitochondria
- secretory granule membrane
- cytosol
- Golgi membrane
- lysosome membrane
- synaptic vesicles
- growth cone
- neurites
- synapse
- autophagic vacuoles
- perikaryon
- axons
- dendrites
- synaptic vesicle fractions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snap29 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fusion
- synaptic vesicle priming
- cilium morphogenesis
- vesicle targeting
- synaptic vesicle fusion to presynaptic membrane
- protein transport
- autophagic vacuole docking
- exocytosis
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
- cytosol
- SNARE complex
- Golgi membrane
- flagellar pocket membrane
- azurophil granule membrane
- autophagic vacuole membrane
- plasma membrane
- autophagic vacuole
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- SNAP receptor activity