Polr3e Gene Summary [Rat]

Predicted to be involved in DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3E (RNA polymerase III subunit E). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Polr3e
Official Name
RNA polymerase III subunit E [Source:RGD Symbol;Acc:1308086]
Ensembl ID
ENSRNOG00000016960
Bio databases IDs NCBI: 361640 Ensembl: ENSRNOG00000016960
Aliases RNA polymerase III subunit E
Synonyms C37, KIAA1452, polymerase (RNA) III (DNA directed) polypeptide E, RGD1308086, RNA polymerase III subunit E, RPC5, SIN
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Polr3e often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • YXXP domain
  • DNA-directed RNA polymerase III subunit RPC5 C-terminal
  • transcription regulator
  • RPC5 protein
  • Sh3 domain binding motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
role in cell
  • apoptosis
  • quantity
  • maturation
  • outgrowth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Polr3e gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • innate immune response
  • defense response to virus
  • tRNA transcription from RNA polymerase III promoter

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • DNA-directed RNA polymerase III complex
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.