Siglec5 Gene Summary [Rat]
Predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to several human genes including SIGLEC5 (sialic acid binding Ig like lectin 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Siglec5 |
| Official Name | sialic acid binding Ig-like lectin 5 [Source:RGD Symbol;Acc:1305432] |
| Ensembl ID | ENSRNOG00000021474 |
| Bio databases IDs | |
| Aliases | sialic acid binding Ig-like lectin 5 |
| Synonyms | mSiglec-F, sialic acid binding Ig-like lectin 5, sialic acid binding Ig-like lectin F, Siglec5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Siglec5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- monosaccharide binding
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- tyrosine internalization motif
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- eosinophilia
role in cell
- phosphorylation in
- expression in
- apoptosis
- proliferation
- number
- cellular infiltration by
- differentiation
- endocytosis by
- endocytosis in
- function
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Plasma Membrane
- lysosome
- cytosol