Cyb561d2 Gene Summary [Rat]

Predicted to enable heme binding activity; transmembrane ascorbate ferrireductase activity; and transmembrane monodehydroascorbate reductase activity. Predicted to be involved in ascorbate homeostasis. Predicted to be located in vesicle. Predicted to be active in endoplasmic reticulum. Orthologous to human CYB561D2 (cytochrome b561 family member D2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cyb561d2
Official Name
cytochrome b561 family, member D2 [Source:RGD Symbol;Acc:1359644]
Ensembl ID
ENSRNOG00000021887
Bio databases IDs NCBI: 363137 Ensembl: ENSRNOG00000021887
Aliases cytochrome b561 family, member D2
Synonyms 101F6, cytochrome b-561 domain containing 2, cytochrome b561 family member D2, cytochrome b561 family, member D2, LOC101928965, Loc56368, TSCytb, TSP10, XXcos-LUCA11.4, XXCOS LUCA115
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cyb561d2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • metal ion oxidising oxidoreductase
  • oxidoreductase
  • oxidoreduction-driven active transporter
  • Cytochrome_b_N
  • enzyme
  • protein binding
  • heme binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • vesicles
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cyb561d2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cytoplasmic vesicle membrane
  • vesicle
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • oxidoreductase activity
  • heme binding

Gene-Specific Assays for Results You Can Trust

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