Opalin Gene Summary [Rat]

Predicted to be involved in regulation of oligodendrocyte differentiation. Predicted to be located in Golgi apparatus. Predicted to be active in cell-cell contact zone and plasma membrane. Orthologous to human OPALIN (oligodendrocytic myelin paranodal and inner loop protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Opalin
Official Name
oligodendrocytic myelin paranodal and inner loop protein [Source:RGD Symbol;Acc:1307776]
Ensembl ID
ENSRNOG00000022386
Bio databases IDs NCBI: 361757 Ensembl: ENSRNOG00000022386
Aliases oligodendrocytic myelin paranodal and inner loop protein
Synonyms HTMP10, oligodendrocytic myelin paranodal and inner loop protein, TMEM10, TMP10
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • cleft palate
regulated by
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cell periphery
  • cellular membrane
  • Plasma Membrane
  • Golgi Apparatus
  • actin filaments
  • intercellular junctions
  • cell-cell contacts
  • paranodal loops
  • myelin sheath inner loop
  • cellular protrusions
  • membrane processes
  • perikaryon
  • axons

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Opalin gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of oligodendrocyte differentiation

Cellular Component

Where in the cell the gene product is active
  • cell-cell contact zone
  • Golgi apparatus
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

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