Opalin Gene Summary [Mouse]
Involved in regulation of oligodendrocyte differentiation. Located in cell-cell contact zone and plasma membrane. Is expressed in brain; spinal cord; and visual system. Orthologous to human OPALIN (oligodendrocytic myelin paranodal and inner loop protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Opalin |
| Official Name | oligodendrocytic myelin paranodal and inner loop protein [Source:MGI Symbol;Acc:MGI:2657025] |
| Ensembl ID | ENSMUSG00000050121 |
| Bio databases IDs | |
| Aliases | oligodendrocytic myelin paranodal and inner loop protein |
| Synonyms | HTMP10, oligodendrocytic myelin paranodal and inner loop protein, TMEM10, TMP10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell periphery
- cellular membrane
- Plasma Membrane
- Golgi Apparatus
- actin filaments
- intercellular junctions
- cell-cell contacts
- paranodal loops
- myelin sheath inner loop
- cellular protrusions
- membrane processes
- perikaryon
- axons
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Opalin gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of oligodendrocyte differentiation
Cellular Component
Where in the cell the gene product is active
- cell-cell contact zone
- Golgi apparatus
- plasma membrane