Rrp7a

Predicted to enable nucleic acid binding activity. Predicted to be involved in cilium disassembly; protein localization to nucleolus; and ribosome biogenesis. Predicted to act upstream of or within blastocyst formation. Predicted to be located in several cellular components, including centrosome; cilium; and nuclear lumen. Predicted to be part of CURI complex; UTP-C complex; and small-subunit processome. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 28. Orthologous to several human genes including RRP7A (ribosomal RNA processing 7 homolog A). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rrp7a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Rrp7a gene, providing context for its role in the cell.