Rpl23a Gene Summary [Rat]
Enables large ribosomal subunit rRNA binding activity. Predicted to be involved in translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL23A (ribosomal protein L23a). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl23a |
| Official Name | ribosomal protein L23a [Source:RGD Symbol;Acc:1304897] |
| Ensembl ID | ENSRNOG00000023344 |
| Bio databases IDs | |
| Aliases | ribosomal protein L23a |
| Synonyms | BC029892, L23A, MDA20, ribosomal protein L23A, uL23 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rpl23a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- binding protein
- rRNA binding
- beta-like import receptor binding domain
- protein binding
- Ribosomal protein L23
- rplW
Pathways
Biological processes and signaling networks where the Rpl23a gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- flu
- recurrent implantation failure
- colorectal cancer
- lymphoma
- lymphomagenesis
role in cell
- cell death
- expression in
- phosphorylation in
- proliferation
- G1 phase
- ubiquitination in
- colony formation
- polyubiquitination in
- Gap 0-Gap 1 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- ribosome
- Nucleus
- cytosol
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rpl23a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- ribosomal large subunit assembly
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytosolic ribosome
- cytoplasm
- cytosol
- cytosolic large ribosomal subunit
- nucleolus
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome
- cadherin binding
- rRNA binding