Tmem176a Gene Summary [Rat]
Predicted to act upstream of or within negative regulation of dendritic cell differentiation. Predicted to be located in membrane. Orthologous to human TMEM176A (transmembrane protein 176A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem176a |
| Official Name | transmembrane protein 176A [Source:RGD Symbol;Acc:1310725] |
| Ensembl ID | ENSRNOG00000023708 |
| Bio databases IDs | |
| Aliases | transmembrane protein 176A |
| Synonyms | 0610011I04Rik, AU040201, GS188, HCA112, Keg2, MS4B1, RGD1310725, transmembrane protein 176A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem176a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- CD20-like family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem176a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of dendritic cell differentiation
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding