Igsf3 Gene Summary [Rat]
Predicted to be involved in lacrimal gland development. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in lacrimal duct obstruction. Orthologous to human IGSF3 (immunoglobulin superfamily member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Igsf3 |
| Official Name | immunoglobulin superfamily, member 3 [Source:RGD Symbol;Acc:1307796] |
| Ensembl ID | ENSRNOG00000023851 |
| Bio databases IDs | |
| Aliases | immunoglobulin superfamily, member 3 |
| Synonyms | 1700016K10RIK, 2810035F16Rik, 4833439O17Rik, EWI-3, immunoglobulin superfamily member 3, immunoglobulin superfamily, member 3, LCDD, mKIAA0466, V8 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Igsf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Immunoglobulin V-Type
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Igsf3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lacrimal gland development
Cellular Component
Where in the cell the gene product is active
- membrane
- cell surface