Scyl3 Gene Summary [Rat]

Predicted to enable identical protein binding activity. Predicted to act upstream of or within inflammatory response; neuron differentiation; and protein localization. Predicted to be located in several cellular components, including Golgi membrane; endoplasmic reticulum; and lamellipodium. Orthologous to human SCYL3 (SCY1 like pseudokinase 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Scyl3
Official Name
SCY1 like pseudokinase 3 [Source:RGD Symbol;Acc:1308992]
Ensembl ID
ENSRNOG00000025318
Bio databases IDs NCBI: 360866 Ensembl: ENSRNOG00000025318
Aliases SCY1 like pseudokinase 3
Synonyms 1200016D23Rik, 6030457O16, PACE-1, RGD1308992, SCY1-like 3 (S. cerevisiae), SCY1 like pseudokinase 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Scyl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Serine/Threonine protein kinases, catalytic domain
  • protein kinase
  • Protein Kinases, catalytic domain
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast carcinoma
  • paralysis
  • gliosis
  • growth failure
role in cell
  • differentiation
  • cell death
  • development
  • number
  • abnormal morphology
  • diameter
  • degeneration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • Endoplasmic Reticulum
  • cytosol
  • Golgi membrane
  • lamellipodia

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Scyl3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • inflammatory response
  • protein localization
  • spinal cord motor neuron differentiation
  • neuron development
  • cell migration

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol
  • endoplasmic reticulum
  • Golgi apparatus
  • Golgi membrane
  • lamellipodium

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • identical protein binding
  • protein binding
  • kinase activity

Gene-Specific Assays for Results You Can Trust

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