Scyl3 Gene Summary [Mouse]
Enables identical protein binding activity. Acts upstream of or within inflammatory response; neuron differentiation; and protein localization. Located in Golgi membrane. Is expressed in retina inner nuclear layer and retina outer nuclear layer. Orthologous to human SCYL3 (SCY1 like pseudokinase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Scyl3 |
| Official Name | SCY1-like 3 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1921385] |
| Ensembl ID | ENSMUSG00000026584 |
| Bio databases IDs | |
| Aliases | SCY1-like 3 (S. cerevisiae) |
| Synonyms | 1200016D23Rik, 6030457O16, PACE-1, RGD1308992, SCY1-like 3 (S. cerevisiae), SCY1 like pseudokinase 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scyl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein kinase
- Protein Kinases, catalytic domain
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Endoplasmic Reticulum
- cytosol
- Golgi membrane
- lamellipodia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Scyl3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- protein localization
- spinal cord motor neuron differentiation
- neuron development
- cell migration
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- endoplasmic reticulum
- Golgi apparatus
- Golgi membrane
- lamellipodium
Molecular Function
What the gene product does at the molecular level
- ATP binding
- identical protein binding
- protein binding
- kinase activity