Adam32 Gene Summary [Rat]
Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; male gonad development; and proteolysis. Predicted to be active in cell surface and plasma membrane. Orthologous to human ADAM32 (ADAM metallopeptidase domain 32). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adam32 |
| Official Name | ADAM metallopeptidase domain 32 [Source:RGD Symbol;Acc:735114] |
| Ensembl ID | ENSRNOG00000025728 |
| Bio databases IDs | |
| Aliases | ADAM metallopeptidase domain 32 |
| Synonyms | ADAM metallopeptidase domain 32, a disintegrin and metallopeptidase domain 32 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Adam32 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Reprolysin family propeptide
- ZnMc
- ADAM cysteine-rich
- peptidase
- Disintegrin
- Reprolysin (M12B) family zinc metalloprotease
- Serine-rich region of AP3B1, clathrin-adaptor complex
- protein binding
- EGF_CA
Pathways
Biological processes and signaling networks where the Adam32 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Adam32 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- binding of sperm to zona pellucida
- male gonad development
- proteolysis
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metalloendopeptidase activity