Wdr36 Gene Summary [Rat]

Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to act upstream of or within regulation of axon extension and retina homeostasis. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in glaucoma and primary open angle glaucoma. Orthologous to human WDR36 (WD repeat domain 36). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Wdr36
Official Name
WD repeat domain 36 [Source:RGD Symbol;Acc:1586463]
Ensembl ID
ENSRNOG00000027355
Bio databases IDs NCBI: 688637 Ensembl: ENSRNOG00000027355
Aliases WD repeat domain 36
Synonyms 5730444A13Rik, GLC1G, TA-WDRP, UTP21, WD repeat domain 36
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Wdr36 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Anaphase-promoting complex subunit 4 WD40 domain
  • WD40 repeats
  • WD domain, G-beta repeat
  • WD40
  • Utp21 specific WD40 associated putative domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • disorder of the nose
  • open angle glaucoma type 1G
  • allergic asthma
  • asthma
  • suicidal ideation
  • chronic sinusitis
regulated by
role in cell
  • processing in
  • extension

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • pre-ribosome
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Wdr36 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit biogenesis
  • rRNA processing
  • visual perception

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • Pwp2p-containing subcomplex of 90S preribosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.