Wdr36 Gene Summary [Mouse]
Acts upstream of or within regulation of axon extension and retina homeostasis. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is expressed in several structures, including adrenal gland; alimentary system; lung; submandibular gland primordium; and testis. Human ortholog(s) of this gene implicated in glaucoma and primary open angle glaucoma. Orthologous to human WDR36 (WD repeat domain 36). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr36 |
| Official Name | WD repeat domain 36 [Source:MGI Symbol;Acc:MGI:1917819] |
| Ensembl ID | ENSMUSG00000038299 |
| Bio databases IDs | |
| Aliases | WD repeat domain 36 |
| Synonyms | 5730444A13Rik, GLC1G, TA-WDRP, UTP21, WD repeat domain 36 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr36 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Anaphase-promoting complex subunit 4 WD40 domain
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- Utp21 specific WD40 associated putative domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- pre-ribosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr36 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit biogenesis
- rRNA processing
- visual perception
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- Pwp2p-containing subcomplex of 90S preribosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding