Coil Gene Summary [Rat]

Predicted to enable disulfide oxidoreductase activity; identical protein binding activity; and snRNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in female germ cell nucleus; fibrillar center; and nuclear body. Predicted to be active in Cajal body. Orthologous to human COIL (coilin). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Coil
Official Name
coilin [Source:RGD Symbol;Acc:62031]
Ensembl ID
ENSRNOG00000000244
Bio databases IDs NCBI: 50998 Ensembl: ENSRNOG00000000244
Aliases coilin
Synonyms CLN80, coilin, p80, p80-coilin
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Coil often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • disulfide oxidoreductase
  • Coilin N-terminus
  • enzyme
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • atopic dermatitis
regulated by
role in cell
  • formation
  • abnormal morphology
  • disruption
  • processing in
  • disassembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • interchromatin granule cluster fractions
  • nuclear fraction
  • soluble fraction
  • fibrillar center
  • Cytoplasm
  • cytosol
  • perinucleolar rings
  • nuclear foci
  • nucleoplasm
  • nucleoli
  • nuclear bodies
  • coiled body
  • Cajal bodies
  • perikaryon
  • cytoplasmic fraction

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Coil gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spliceosomal snRNP assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear body
  • membrane
  • Cajal body
  • cytosol
  • nucleolus
  • fibrillar center
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • U1 snRNA binding
  • U2 snRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.