Gpr179 Gene Summary [Rat]

This gene encodes a member of the glutamate receptor subfamily of G protein-coupled receptors. The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. [provided by RefSeq, Apr 2012]

Details

Type
Protein Coding
Official Symbol
Gpr179
Official Name
G protein-coupled receptor 179 [Source:RGD Symbol;Acc:1560033]
Ensembl ID
ENSRNOG00000029245
Bio databases IDs NCBI: 287657 Ensembl: ENSRNOG00000029245
Aliases G protein-coupled receptor 179
Synonyms 5330439C02Rik, CSNB1E, GPR158L, GPR158L1, G protein-coupled receptor 179, LOC100290717, RGD1560033
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gpr179 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • protein binding
  • 7 transmembrane sweet-taste receptor of 3 GCPR
  • seven-transmembrane G protein-coupled receptor superfamily
  • EGF_CA

Pathways

Biological processes and signaling networks where the Gpr179 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • congenital stationary night blindness
  • optic atrophy
  • congenital stationary night blindness type 1E
  • retinal dystrophy
  • recessive congenital stationary night blindness
  • GPR179-related retinopathy
  • aggressive periodontitis
  • congenital stationary night blindness type 1B
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • dendrite tip
  • cellular membrane
  • postsynaptic membrane
  • cell tip
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gpr179 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • visual perception

Cellular Component

Where in the cell the gene product is active
  • dendrite
  • postsynaptic membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.