Gpr179 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Involved in visual perception. Acts upstream of or within protein localization to plasma membrane and response to light stimulus. Located in dendrite terminus. Is active in cell tip; dendrite; and postsynaptic membrane. Used to study congenital stationary night blindness 1E. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1E. Orthologous to human GPR179 (G protein-coupled receptor 179). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Gpr179
Official Name
G protein-coupled receptor 179 [Source:MGI Symbol;Acc:MGI:2443409]
Ensembl ID
ENSMUSG00000070337
Bio databases IDs NCBI: 217143 Ensembl: ENSMUSG00000070337
Aliases G protein-coupled receptor 179
Synonyms 5330439C02Rik, CSNB1E, GPR158L, GPR158L1, G protein-coupled receptor 179, LOC100290717, RGD1560033
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr179 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • protein binding
  • 7 transmembrane sweet-taste receptor of 3 GCPR
  • seven-transmembrane G protein-coupled receptor superfamily
  • EGF_CA

Pathways

Biological processes and signaling networks where the Gpr179 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • congenital stationary night blindness
  • optic atrophy
  • congenital stationary night blindness type 1E
  • retinal dystrophy
  • recessive congenital stationary night blindness
  • GPR179-related retinopathy
  • aggressive periodontitis
  • congenital stationary night blindness type 1B
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • dendrite tip
  • cellular membrane
  • postsynaptic membrane
  • cell tip
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr179 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • visual perception

Cellular Component

Where in the cell the gene product is active
  • dendrite
  • postsynaptic membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.