Serinc1 Gene Summary [Rat]
Enables acetyltransferase activator activity; enzyme binding activity; and protein-macromolecule adaptor activity. Involved in membrane biogenesis; phosphatidylserine metabolic process; and sphingolipid metabolic process. Located in endoplasmic reticulum membrane and plasma membrane. Orthologous to human SERINC1 (serine incorporator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Serinc1 |
| Official Name | serine incorporator 1 [Source:RGD Symbol;Acc:727843] |
| Ensembl ID | ENSRNOG00000029360 |
| Bio databases IDs | |
| Aliases | serine incorporator 1 |
| Synonyms | 1500011D18Rik, AIGP-2, LRRGT00191, mKIAA1253, serine incorporator 1, TDE1L, TDE2, TMS-2, Tumor diff exp 2, tumour diff exp 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Serinc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- enzyme binding
- Serine incorporator (Serinc)
- protein binding
- enzyme activator activity
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Serinc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylserine metabolic process
- phospholipid biosynthetic process
- sphingolipid metabolic process
- membrane biogenesis
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein binding, bridging