Enox2 Gene Summary [Rat]

Predicted to enable RNA binding activity and oxidoreductase activity. Predicted to be involved in electron transport chain and ultradian rhythm. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Orthologous to human ENOX2 (ecto-NOX disulfide-thiol exchanger 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Enox2
Official Name
ecto-NOX disulfide-thiol exchanger 2 [Source:RGD Symbol;Acc:1563643]
Ensembl ID
ENSRNOG00000030622
Bio databases IDs NCBI: 302817 Ensembl: ENSRNOG00000030622
Aliases ecto-NOX disulfide-thiol exchanger 2
Synonyms APK1, COVA1, Cytosolic ovarian carcinoma antigen 1, ecto-NOX disulfide-thiol exchanger 2, RGD1563643, TNOX
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Enox2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • capsaicin
  • RANBP3L
  • SRPK2
  • 4,11-bis(2-(2-chloroacetamidine)ethylamino)anthra[2,3-b]thiophene-5,10-dione
  • PRKAG3

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • Cytoplasm
  • Extracellular Space
  • Nucleus
  • cytosol
  • plasma membrane extracellular face

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Enox2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • electron transport chain
  • ultradian rhythm

Cellular Component

Where in the cell the gene product is active
  • external side of plasma membrane
  • cytosol
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • oxidoreductase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.