Enox2 Gene Summary [Mouse]
Predicted to enable RNA binding activity and oxidoreductase activity. Predicted to be involved in electron transport chain and ultradian rhythm. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. Is expressed in central nervous system; olfactory epithelium; and retina. Orthologous to human ENOX2 (ecto-NOX disulfide-thiol exchanger 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Enox2 |
| Official Name | ecto-NOX disulfide-thiol exchanger 2 [Source:MGI Symbol;Acc:MGI:2384799] |
| Ensembl ID | ENSMUSG00000031109 |
| Bio databases IDs | |
| Aliases | ecto-NOX disulfide-thiol exchanger 2 |
| Synonyms | APK1, COVA1, Cytosolic ovarian carcinoma antigen 1, ecto-NOX disulfide-thiol exchanger 2, RGD1563643, TNOX |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Enox2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- Extracellular Space
- Nucleus
- cytosol
- plasma membrane extracellular face
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Enox2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- electron transport chain
- ultradian rhythm
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- cytosol
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- RNA binding
- oxidoreductase activity