Fam227b Gene Summary [Rat]
Orthologous to human FAM227B (family with sequence similarity 227 member B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam227b |
| Official Name | family with sequence similarity 227, member B [Source:RGD Symbol;Acc:1359452] |
| Ensembl ID | ENSRNOG00000037124 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 227, member B |
| Synonyms | 4930525F21Rik, C15orf33, family with sequence similarity 227 member B, family with sequence similarity 227, member B, RGD1359452 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fam227b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- epithelial basal cell carcinoma
- epithelial cancer
- nontoxic goiter
- lung adenocarcinoma
- non-insulin-dependent diabetes mellitus
- breast carcinoma
- multinodular goiter
- oral cancer
- human papilloma virus infection
regulated by
- calcitriol
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria