Ahcyl2 Gene Summary [Rat]

Predicted to be involved in S-adenosylmethionine cycle. Predicted to be located in intracellular membrane-bounded organelle and neuron projection. Predicted to be active in cytosol. Orthologous to human AHCYL2 (adenosylhomocysteinase like 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ahcyl2
Official Name
adenosylhomocysteinase-like 2 [Source:RGD Symbol;Acc:1564895]
Ensembl ID
ENSRNOG00000039300
Bio databases IDs NCBI: 312192 Ensembl: ENSRNOG00000039300
Aliases adenosylhomocysteinase-like 2
Synonyms 4631427C17Rik, adenosylhomocysteinase-like 2, ADOHCYASE3, IRBIT2, KIAA0828, mKIAA0828, RGD1564895, S-adenosylhomocysteine hydrolase-like 2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ahcyl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rossmann-fold NAD(P)(+)-binding proteins
  • S-adenosyl-L-homocysteine hydrolase, NAD binding domain
  • S-adenosyl-L-homocysteine hydrolase
  • adenosylhomocysteinase
  • TrkA-N domain
  • enzyme
  • protein binding

Pathways

Biological processes and signaling networks where the Ahcyl2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal cancer
  • acute myeloid leukemia
  • tuberculosis
  • dementia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • intracellular membrane-bounded organelle
  • cytosol
  • neurites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ahcyl2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • S-adenosylmethionine cycle
  • one-carbon metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • endoplasmic reticulum
  • neuron projection

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • adenosylhomocysteinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.