Ecd Gene Summary [Rat]
Predicted to enable histone acetyltransferase binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within fibroblast proliferation and regulation of G1/S transition of mitotic cell cycle. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ECD (ecdysoneless cell cycle regulator). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ecd |
| Official Name | ecdysoneless cell cycle regulator [Source:RGD Symbol;Acc:1565023] |
| Ensembl ID | ENSRNOG00000042253 |
| Bio databases IDs | |
| Aliases | ecdysoneless cell cycle regulator |
| Synonyms | 5730461K03Rik, ecdysoneless cell cycle regulator, GCR2, HSGT1, LOC361098, RGD1565023, SGT1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ecd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- SGT1 protein
- protein binding
- histone acetyltransferase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- stuttering
role in cell
- phosphorylation in
- cell death
- proliferation
- migration
- growth
- invasion
- colony formation in
- colony survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ecd gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fibroblast proliferation
- RNA splicing
- regulation of G1/S transition of mitotic cell cycle
- mRNA processing
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone acetyltransferase binding
- protein binding