ECD Gene Summary [Human]
Enables histone acetyltransferase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ECD |
| Official Name | ecdysoneless cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:17029] |
| Ensembl ID | ENSG00000122882 |
| Bio databases IDs | |
| Aliases | ecdysoneless cell cycle regulator |
| Synonyms | 5730461K03Rik, ecdysoneless cell cycle regulator, GCR2, HSGT1, LOC361098, RGD1565023, SGT1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ECD often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- SGT1 protein
- protein binding
- histone acetyltransferase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- stuttering
role in cell
- phosphorylation in
- cell death
- proliferation
- migration
- growth
- invasion
- colony formation in
- colony survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ECD gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fibroblast proliferation
- RNA splicing
- regulation of G1/S transition of mitotic cell cycle
- mRNA processing
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone acetyltransferase binding
- protein binding