Glyctk Gene Summary [Rat]

Enables glycerate kinase activity. Predicted to be involved in fructose catabolic process and protein phosphorylation. Is active in cytosol. Human ortholog(s) of this gene implicated in D-glyceric aciduria. Orthologous to human GLYCTK (glycerate kinase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Glyctk
Official Name
glycerate kinase [Source:RGD Symbol;Acc:1591498]
Ensembl ID
ENSRNOG00000046307
Bio databases IDs NCBI: 684314 Ensembl: ENSRNOG00000046307
Aliases glycerate kinase
Synonyms 6230410P16RIK, C430006L12, glycerate kinase, HBeAgBP4A, HBEBP2, HBEBP4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Glyctk often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • MOFRL family
  • glycerate kinase
  • protein binding
  • Domain of unknown function (DUF4147)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • D-glyceric aciduria
regulated by
regulates
  • D-fructose

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • Mitochondria
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Glyctk gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • mitochondrion
  • cytosol
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • glycerate kinase activity

Gene-Specific Assays for Results You Can Trust

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