Glyctk Gene Summary [Mouse]
Predicted to enable glycerate kinase activity. Involved in fructose catabolic process. Located in mitochondrion. Is expressed in alimentary system; cerebral cortex; liver; and urinary system. Human ortholog(s) of this gene implicated in D-glyceric aciduria. Orthologous to human GLYCTK (glycerate kinase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Glyctk |
| Official Name | glycerate kinase [Source:MGI Symbol;Acc:MGI:2444085] |
| Ensembl ID | ENSMUSG00000020258 |
| Bio databases IDs | |
| Aliases | glycerate kinase |
| Synonyms | 6230410P16RIK, C430006L12, glycerate kinase, HBeAgBP4A, HBEBP2, HBEBP4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Glyctk often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- MOFRL family
- glycerate kinase
- protein binding
- Domain of unknown function (DUF4147)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Glyctk gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
- cytosol
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- glycerate kinase activity