Mrps22 Gene Summary [Rat]
Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 5 and ovarian dysgenesis 7. Orthologous to human MRPS22 (mitochondrial ribosomal protein S22). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrps22 |
| Official Name | mitochondrial ribosomal protein S22 [Source:RGD Symbol;Acc:1585674] |
| Ensembl ID | ENSRNOG00000047984 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein S22 |
| Synonyms | 3100002P07Rik, C3orf5, COXPD5, GIBT, GK002, mitochondrial ribosomal protein S22, mS22, ODG7, RPMS22, RT22 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrps22 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- protein binding
- Mitochondrial 28S ribosomal protein S22
Pathways
Biological processes and signaling networks where the Mrps22 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- ovarian dysgenesis type 7
- obesity
- attached earlobe
- male pattern hair loss
- combined oxidative phosphorylation deficiency 5
- hereditary disorder
- androgenic alopecia
- bipolar disorder
- alopecia
- mitochondrial disorder
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mrps22 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial ribosome
- mitochondrial small ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- structural constituent of ribosome