Dppa3 Gene Summary [Rat]
Predicted to enable methylated histone binding activity. Predicted to be involved in epigenetic programing of female pronucleus. Predicted to act upstream of or within embryonic cleavage. Predicted to be located in chromatin; cytoplasm; and pronucleus. Predicted to be active in nucleus. Orthologous to human DPPA3 (developmental pluripotency associated 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dppa3 |
| Official Name | developmental pluripotency-associated 3 [Source:RGD Symbol;Acc:1310932] |
| Ensembl ID | ENSRNOG00000022950 |
| Bio databases IDs | |
| Aliases | developmental pluripotency-associated 3 |
| Synonyms | 2410075G02Rik, developmental pluripotency-associated 3, PCG7, PGC7, STELLA |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dppa3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone binding
- PGC7/Stella/Dppa3 domain
- protein binding activity, bridging
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
- pronucleus
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dppa3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- male pronucleus
- cytoplasm
- female pronucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- methylated histone residue binding