Inpp5b

Predicted to enable inositol-1,4,5-trisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to act upstream of or within several processes, including flagellated sperm motility; in utero embryonic development; and regulation of protein processing. Predicted to be located in early endosome membrane and phagocytic vesicle membrane. Predicted to be active in cytosol; membrane; and neuron projection. Orthologous to human INPP5B (inositol polyphosphate-5-phosphatase B). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Inpp5b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Inpp5b gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Inpp5b gene, providing context for its role in the cell.