Islr2 Gene Summary [Rat]
Predicted to be involved in positive regulation of axon extension. Predicted to be located in membrane. Predicted to be active in cell surface. Orthologous to human ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Islr2 |
| Official Name | immunoglobulin superfamily containing leucine-rich repeat 2 [Source:RGD Symbol;Acc:6497037] |
| Ensembl ID | ENSRNOG00000050714 |
| Bio databases IDs | |
| Aliases | immunoglobulin superfamily containing leucine-rich repeat 2 |
| Synonyms | B930052A04Rik, immunoglobulin superfamily containing leucine-rich repeat 2, LINX, Mbu-3, mKIAA1465 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Islr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Leucine rich repeat
- Leucine rich repeat C-terminal domain
- protein binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Islr2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- positive regulation of axon extension
Cellular Component
Where in the cell the gene product is active
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding