Hpcal4 Gene Summary [Rat]

Enables calcium channel regulator activity and protein domain specific binding activity. Predicted to be involved in regulation of signal transduction. Predicted to act upstream of or within response to heat. Orthologous to human HPCAL4 (hippocalcin like 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Hpcal4
Official Name
hippocalcin-like 4 [Source:RGD Symbol;Acc:708491]
Ensembl ID
ENSRNOG00000050983
Bio databases IDs NCBI: 50872 Ensembl: ENSRNOG00000050983
Aliases hippocalcin-like 4
Synonyms hippocalcin-like 4, HLP4, NVJP2, NVL-2, NVP-2, VILIP-2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hpcal4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EF-hand, calcium binding motif
  • EF-hand domain
  • Dockerin type I domain
  • EF-hand domain pair
  • EF hand
  • calcium ion binding
  • EFh
  • protein domain specific binding
  • protein binding
  • calcium channel regulator
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • progression free survival
regulated by
  • beta-estradiol
  • testosterone
  • KRAS
  • EGFR
  • MirBART2
  • JAK1/2
  • SNCA
  • NRF1
  • bardoxolone methyl
  • memantine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Hpcal4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • central nervous system development

Molecular Function

What the gene product does at the molecular level
  • protein domain specific binding
  • protein binding
  • calcium ion binding
  • calcium channel regulator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.