Klra1 Gene Summary [Rat]
Predicted to enable signaling receptor activity. Predicted to be involved in cell adhesion. Predicted to be located in plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Klra1 |
| Official Name | killer cell lectin-like receptor, subfamily A, member 1 [Source:RGD Symbol;Acc:1359586] |
| Ensembl ID | ENSRNOG00000051489 |
| Bio databases IDs | |
| Aliases | killer cell lectin-like receptor, subfamily A, member 1 |
| Synonyms | 5E6, A1, CH29-493D4.3, Chok, Cmv-1, Gm15854, killer cell lectin-like receptor, subfamily A, member 1, killer cell lectin-like receptor subfamily A, member 10, killer cell lectin-like receptor subfamily A, member 13, pseudogene 2, killer cell lectin-like receptor subfamily A, member 21, killer cell lectin-like receptor, subfamily A, member 3, killer cell lectin-like receptor, subfamily A, member 4, killer cell lectin-like receptor, subfamily A, member 5, killer cell lectin-like receptor, subfamily A, member 6, killer cell lectin-like receptor, subfamily A, member 7, killer cell lectin-like receptor, subfamily A, member 8, killer cell lectin-like receptor subfamily A, member 9, Klra1, Klra10, Klra13-ps2, Klra2, Klra21, Klra22, Klra3, Klra32, Klra33, Klra5, Klra6, Klra7, Klra8, Klra9, Klra-ps1, LGL-1, LOC100038895, LOC100038897, LOC100862408, LOC100862410, LOC105247435, LOC108167383, LOC108167384, LOC108167386, LOC108167393, LOC115486444, Ly49a, Ly49c, Ly49c/i, Ly-49d, Ly49e, Ly49f, Ly49g, Ly-49G.1, Ly49g2, Ly-49G.2, Ly-49G.3, Ly49g4, Ly49G.4, Ly49H, Ly49I, LY49I1, Ly49i2, Ly49i6, Ly49J, Ly49u, Ly49v, Nk-2, NK-2.1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Klra1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- signaling receptor activity
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- cytoplasmic domain
- immunoreceptor tyrosine-based inhibition motif
- ectodomain
- Lectin C-type domain
- Ly49-like protein, N-terminal region
- protein binding
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Klra1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- cancer
- infection
- Alzheimer disease
- infection by Murine cytomegalovirus
role in cell
- proliferation
- quantity
- apoptosis
- migration
- production in
- killing
- cytolysis
- binding
- hyporesponsiveness
- degranulation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- membrane surface
- cellular membrane
- plasma membrane extracellular face